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潮州市(饶平县、湘桥区、潮安区)
阿克苏地区(乌什县、阿瓦提县、拜城县、阿克苏市、柯坪县、温宿县、新和县、沙雅县、库车市)

  海口4月19日电(记者符宇群)“海口市是一座名副其实的历史文化名城。”海口市人民政府副秘书长黄燕18日在海南省新闻办公室召开的新闻发布会上说,海口现共有各级文物保护单位152处。海口将推进文物活化利用工作,重点保护传承好东坡文化、丘浚文化、海瑞文化、海洋文化、革命文化等地方特色文化。

  广州4月19日电(记者蔡敏婕)国家药品监督管理局官网18日发布消息称,近日批准依若奇单抗注射液上市,适用于中度至重度斑块状银屑病的成年患者的治疗。

  银屑病俗称“牛皮癣”,是一种慢性、复发性、炎症性、系统性的皮肤疾病,典型皮损临床表现为鳞屑性红斑或斑块。银屑病除了影响皮肤,还可能影响全身各个器官系统,比如部分银屑病患者伴有关节炎,部分银屑病患者合并高血压、糖尿病等代谢相关疾病。

  根据统计,中国银屑病患病人数超过670万,并呈逐年增加趋势,需要长期用药治疗,整体疾病负担重。

  根据国家药品监督管理局官网信息,依若奇单抗注射液适用于对环孢素、甲氨蝶呤等其他系统性治疗或补骨脂素和紫外线A不应答、有禁忌或无法耐受的中度至重度斑块状银屑病的成年患者的治疗。

  依若奇单抗针对中重度斑块状银屑病受试者共开展了5项临床研究。根据中山康方生物医药有限公司提供的研究结果显示,接受依若奇单抗长期维持治疗,治疗16周因皮肤疾病困扰对患者生活质量的影响程度下降超过55%,治疗第52周进一步下降至超过65%。

  北京大学人民医院教授张建中表示,依若奇单抗开启了IL-12/IL-23单抗的国产化新时代。多项临床研究显示,依若奇单抗长期可稳定维持,改善皮损的同时提高患者生活质量。依若奇单抗给药频次少,每年仅需4次,有助于提高患者的用药依从性,进而长期稳定的提升治疗效果和生活质量。(完)新闻结尾 功高权重无弹窗,带你走进另类轻松幽默的课堂氛围,体验学习的的相关文章
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