Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82

Deprecated: strpos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /www/wwwroot/4-17ll.com/label.php on line 82
欲乱美女诗涵番外5:助你轻松实现生育梦想,开启幸福家庭新篇章!
随机图片

欲乱美女诗涵番外5:助你轻松实现生育梦想,开启幸福家庭新篇章!

更新时间: 浏览次数: 938

 
欲乱美女诗涵番外5:助你轻松实现生育梦想,开启幸福家庭新篇章!123456已更新(123456已更新)



Random Image



欲乱美女诗涵番外5:助你轻松实现生育梦想,开启幸福家庭新篇章!在线观看电话:(1)123456(点击咨询)(2)123456(点击咨询)









欲乱美女诗涵番外5:助你轻松实现生育梦想,开启幸福家庭新篇章!24小时热线(1)123456(点击咨询)(2)123456(点击咨询)





欲乱美女诗涵番外5:助你轻松实现生育梦想,开启幸福家庭新篇章!24小时在线观看电话《今日发布》

欲乱美女诗涵番外5:助你轻松实现生育梦想,开启幸福家庭新篇章!附近上门电话









7天24小时人工电话为您、欲乱美女诗涵番外5:助你轻松实现生育梦想,开启幸福家庭新篇章!团队在调度中心的统筹调配下,线下专业及各地区人员团队等专属,整个报修流程规范有序,后期同步跟踪查询公开透明




欲乱美女诗涵番外5:助你轻松实现生育梦想,开启幸福家庭新篇章!在线观看查询









欲乱美女诗涵番外5:助你轻松实现生育梦想,开启幸福家庭新篇章!24小时在线观看电话:

 娄底市(冷水江市、双峰县、涟源市、新化县、娄星区)





泰安市(岱岳区、泰山区、东平县、肥城市、新泰市、宁阳县)









襄阳市(襄州区、老河口市、襄城区、谷城县、保康县、南漳县、宜城市、樊城区、枣阳市)









南宁市(武鸣区、邕宁区、青秀区、兴宁区、宾阳县、西乡塘区、隆安县、江南区、良庆区、横州市、上林县、马山县)  湘西土家族苗族自治州(保靖县、古丈县、永顺县、泸溪县、吉首市、花垣县、龙山县、凤凰县)









乐山市(峨眉山市、沙湾区、五通桥区、金口河区、市中区、峨边彝族自治县、夹江县、沐川县、马边彝族自治县、犍为县、井研县)









澳门特别行政区









甘孜藏族自治州(新龙县、丹巴县、石渠县、道孚县、泸定县、巴塘县、康定市、德格县、炉霍县、色达县、甘孜县、白玉县、九龙县、理塘县、得荣县、雅江县、乡城县、稻城县)莆田市(秀屿区、荔城区、涵江区、仙游县、城厢区)









延边朝鲜族自治州(珲春市、安图县、和龙市、汪清县、图们市、龙井市、延吉市、敦化市)  芜湖市(繁昌区、弋江区、无为市、南陵县、鸠江区、镜湖区、湾沚区)









漯河市(郾城区、临颍县、召陵区、源汇区、舞阳县)









湖州市(南浔区、德清县、长兴县、吴兴区、安吉县)









嘉峪关市十堰市(丹江口市、张湾区、茅箭区、郧西县、竹山县、房县、竹溪县、郧阳区)









宿迁市(泗洪县、宿城区、沭阳县、宿豫区、泗阳县)









伊犁哈萨克自治州(霍尔果斯市、新源县、巩留县、尼勒克县、伊宁县、霍城县、伊宁市、特克斯县、昭苏县、察布查尔锡伯自治县、奎屯市)









阿克苏地区(温宿县、库车市、乌什县、柯坪县、新和县、沙雅县、阿瓦提县、拜城县、阿克苏市)









鄂州市(梁子湖区、鄂城区、华容区)









昌吉回族自治州(阜康市、木垒哈萨克自治县、呼图壁县、玛纳斯县、吉木萨尔县、奇台县、昌吉市)









新余市(分宜县、渝水区)

热点栏目自选股数据中心行情中心资金流向模拟交易客户端

  转自:北京商报

  作为国内疫苗行业的标杆企业,智飞生物(300122)2024年交出了一份令市场震惊的成绩单:全年营业收入260.7亿元,同比腰斩(-50.74%);归母净利润20.18亿元,降幅达74.99%。更值得警惕的是,经营性现金流首次转负至-44.14亿元,资产负债率攀升至62.3%,创下近五年新高。这种营收、利润、现金流“三杀”的局面背后,是其核心代理业务的断崖式下跌。

  连续3个季度亏损

  4月22日,智飞生物披露2024年年报及2025年一季报。财务数据显示,2024年,智飞生物实现营业收入260.7亿元,同比下降50.74%;实现归属净利润20.18亿元,同比下降74.99%。分季度来看,智飞生物自2024年三季度起净利开始出现亏损,一至四季度净利分别为14.58亿元、7.77亿元、-8369.64万元、-1.32亿元。

  今年一季度,智飞生物净利继续下滑,且出现亏损。财务数据显示,公司营业收入为23.74亿元,同比下降79.16%;归属净利润为-3.05亿元,同比由盈转亏。资料显示,智飞生物共有15种产品上市,其中1种产品附条件上市,包括预防流脑、宫颈癌、肺炎、流感、轮状病毒、带状疱疹等传染病的疫苗产品,也涵盖提供结核感染诊断、预防、治疗有效解决方案的药品。

  在2024年年报中,智飞生物表示,报告期内,公司业绩显著承压,主要受行业政策调整、民众接种意愿下降、市场需求变化等多重因素影响,公司主要产品的市场推广销售工作未达预期。报告期内,多家疫苗行业上市公司业绩均呈现大幅度下降情况,公司业绩波动与行业整体趋势一致。

  核心代理业务断崖式下跌是业绩滑坡的直接推手。智飞生物代理的默沙东HPV疫苗,长期以来为公司贡献了高额利润。不过,2024年,智飞生物代理的默沙东疫苗的批签发量均出现下降。数据显示,2024年,默沙东四价HPV疫苗全年批签发量为46.6万支,同比下降95.49%;九价HPV疫苗全年批签发量为3114.08万支,同比下降14.8%。此外,智飞生物代理的五价轮状疫苗、进口23价肺炎疫苗、灭活甲肝疫苗的全年批签发量均出现不同程度下滑。

  北京中医药大学卫生健康法治研究与创新转化中心主任邓勇在接受北京商报记者采访时表示,整体来看,疫苗企业在市场竞争、产品价格、研发创新等方面都面临着较大压力,需要不断调整经营策略和发展方向以应对挑战。

  业绩承压的同时,智飞生物在二级市场的表现也不理想,股价也一路走低。4月22日,智飞生物盘中一度跌逾8%,最终收跌6.86%,收盘价为20.23元/股,总市值为484.3亿元,较2021年的历史高点已跌去逾八成。

  针对公司相关问题,北京商报记者向智飞生物方面发去采访函,不过截至记者发稿,未收到公司回复。

  发力自主产品

  在智飞生物看来,尽管行业短期承压,但在政策支持与技术创新的驱动下,国内疫苗市场仍具有较大发展潜力与商业机遇。未来,随着民众接种意愿不断提升,创新疫苗及成人疫苗加速普及,疫苗市场有望实现扩容升级,激发强劲的增长潜力。

  目前,默沙东的HPV疫苗已经率先从女性市场开拓至男性市场,强调“男女共防”。4月14日,默沙东宣布,公司的九价HPV疫苗佳达修9多项新适应证已获得国家药品监督管理局的上市批准,适用于16—26岁男性接种。这一获批使该疫苗成为中国境内首个且目前唯一获批、可适用于适龄男性女性接种的九价HPV疫苗。更早之前,今年1月,默沙东四价HPV疫苗也获批用于9—26岁男性接种,成为国内首个可适用于男性的HPV疫苗。不过,男性适应证能为智飞生物带来多少的批签发量以及业绩增长,仍需要观察。

  另一方面,国产二价HPV疫苗的上市对智飞生物同样带来冲击。目前,万泰生物的馨可宁、沃森生物的沃泽惠,这两款二价HPV疫苗已经在国内上市。尽管不如四价HPV、九价HPV预防的病毒型号全面。但二价HPV疫苗主要针对与宫颈癌最密切相关的HPV16和18型,这两种型别导致了大约84.5%的宫颈癌。因此,在预防宫颈癌方面,二价疫苗的效果尚可。

  此外,自主产品2024年为智飞生物贡献了4.53%的收入,收入总额为11.82%,同比增长14.98%,毛利率超过80%。形成对比的是,代理产品的毛利率仅为24.98%。近些年,智飞生物也在发力自主产品的研发。

  智飞生物表示,公司布局丰富多元的自主产品在研管线,持续加大科研创新投入与资源整合力度,以实现创新技术向社会效益和商业价值的加速转化。公司持续优化市场策略以更好地适应市场趋势和客户需求,同时严格把控经营风险,确保公司稳健发展。

  最为行业关注的是,2025年3月,公司以增资形式实现对宸安生物的控股,拓展GLP-1、胰岛素类似物等领域自研管线布局。最新财报显示,司美格鲁肽注射液的超重/肥胖适应证的三期临床正在进行中。

  北京商报记者丁宁

  美联储理事AdrianaKugler称关税可能会对价格构成上行压力,对经济的影响也将超出之前的预期。

  Kugler重申她支持维持借贷成本不变,直至通胀风险减弱、经济活动和就业保持稳定。

  Kugler周二在为一场大学活动准备的演讲中表示,“当前经济面临加剧的不确定性,通胀存在上行风险,而就业则面临下行风险。”

  “本月我们获悉关税上调幅度明显高于之前的预期,”她说,“因此,关税对经济的影响和相关不确定性也可能比预期更大。”

  Kugler的讲话主要集中在货币政策传导。她强调了美联储的政策对经济产生影响需要时间,并补充说正是这种滞后使得官员必须主动了解不同冲击产生的影响。

  “重要的是货币政策制定者广泛研究所有可用信息,包括基于市场的指标、调查和坊间报告,以尽早了解经济状况。因为正如我所讨论的那样,政策发挥作用需要时间,”Kugler说。

欲乱美女诗涵番外5:助你轻松实现生育梦想,开启幸福家庭新篇章!的相关文章 老板拒售变味卤鸭转身躲过一劫的相关文章
中央巡视组已进驻6省区 组长亮相
百余名受资助湖南学生自发送别坤叔
梅州客家4月20日主场迎战深圳新鹏城
金饰价格涨至1007元
男子手拎981株罂粟苗入境被查
马拉多纳医生否认与其发生性关系
  • 友情链接:
  • 森林狼老将康利谈备战湖人 国际原子能机构总干事抵达伊朗 朱立伦子弟兵轰民进党政治追杀 苹果和英伟达悬着的心怎么落下来 女教师上海街头怒怼“偷拍老法师” F勒布伦无缘乒乓球世界杯16强 胡锡进:A股请不要被特朗普团队骗了 纳斯达克中国金龙指数盘初跌超2.5% 外援布彭扎意外坠亡 浙江队回应 刘耀文回应和张真源冷战 中国驻英使馆回应英国钢企问题